Hydrogel-based Material Systems Toward Therapeutic Applications

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Submission Deadline: 30 November 2024

Guest Editor

Prof. Dr. Qihui Zhou

School of Rehabilitation Sciences and Engineering, University of Health and Rehabilitation Sciences, Qingdao 266071, China.

Research Interest: Biomaterials, hydrogels, nanomedicine, drug delivery system, tissue repair and regeneration, organ function rehabilitation



Hydrogels, which are three-dimensional networks of water-absorbing polymers, have aroused great concern in treatment applications owing to their tunable characteristics such as their good biocompatibility and biodegradation, natural extracellular matrix-like structure, tunable mechanical properties, suitable diffusion nature due to their elastic networks, wound exudate absorption, and high cargo-loading efficiency. With their gaining popularity in biomedical applications, many novel and biomimetic structures from 1D to 3D level based on hydrogels (e.g., micro/nanogels, micro/nanofibers, microneedle patch, scaffold) are designed and prepared using advanced micro and nano-fabrication techniques, extending their bioapplication. In addition, due to the flexibility to be designed with stimuli-responsive features, hydrogel-based material systems can be controlled to trigger network assembly/disassembly to release loaded drugs/bio-factors via responding to external stimuli (e.g., temperature, light, magnetic fields, mechanical forces, etc.) and internal physiological conditions, such as glucose, pH, enzymatic activity, and redox. In terms of these merits, hydrogel-based material systems have been widely applied in treating various diseases, tissue repair and regeneration, as well as rehabilitation, laying the foundation for future clinic translations.

Keywords: hydrogels, biomimetic structures, drug release, therapeutic applications, tissue repair, regenerative medicine, rehabilitation

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Recent Advances in Drug Delivery Systems

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Submission Deadline: 31 December 2024


Guest Editor:   

Prof. Dr. Gholamhossein Sodeifian
Department of Chemical Engineering, Faculty of Engineering, Laboratory of Supercritical Fluids and Nanotechnology, Modeling and Simulation Center, University of Kashan, Kashan 87317-53153, Iran
Research Interest: supercritical fluid technology; polymers; solubility; drug delivery system; extraction; particle formation; nanotechnology; reaction; modeling; optimization.



Drug delivery systems describe technologies that carry drugs into or throughout the body. These technologies include the method of delivery, such as a pill that you swallow or a vaccine that is injected. Drug delivery systems can also describe the way that drugs are ‘packaged’—like a micelle or a nanoparticle—that protects the drug from degradation and allows it to travel wherever it needs to go in the body. The field of drug delivery has advanced dramatically in the past few decades, and even greater innovations are anticipated in the coming years. For instance, biocompatible drug delivery systems are alternative ones that can be used by both nanoparticles and liposomes. In this special issue, authors and researchers can submit their manuscripts focusing on different drug delivery systems design, nanoparticles and their synthesis by green methods, modeling by molecular dynamic simulation, biopolymers, application of supercritical fluid technology, etc.


Keywords: Drug delivery systems, Nanoparticles, Molecular dynamic simulation, Micelles, Liposomes, Biomedicine, Biopolymers, Targeted drug delivery systems

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